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Pei L., Shen X., Yan Y., et al., Virtual Screening of the MultiPathway and MultiGene Regulatory Molecular Mechanism of Dachengqi Decoction in the Treatment of Stroke Based on Network Pharmacology, Combinatorial Chemistry & High Throughput Screening 23, no

The small molecule has a strong affinity for the GIP receptor and inhibition of GIP-stimulated cAMP production in vitro ( Table 1 )

The supramammillary nucleus, located in the hypothalamus, is a new candidate that appears to be responsible for GLP-1 mediated anxiety effects because selective activation of GLP-1Rs in this nucleus by exendin-4 resulted in intensified anxiety-like behavior both in male and female rats

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BMJ 347 , f5934 (2013)

doi: 10.1007/s13300-012-0014-7