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Preliminary data point toward beneficial effects of GIP agonism, as reported in findings from the SURPASS program that tirzepatide reduced UACR and slowed down eGFR declined in comparison with both placebo (53) and comparator drugs including insulin glargine (74, 75)

Weight loss typically occurs gradually over the following months

People on GLP-1s medications or any caloric-deficit diet [can] face challenges such as nutrient deficiencies, reduced appetite, and muscle loss

cms.gov/medicare/coverage/prescription-drug-coverage/medicare-glp-1-bridge American Diabetes Association

Originally developed for diabetes management, these GLP-1 receptor agonists have shown impressive results in clinical trials helping many patients lose 1521% of their body weight under controlled study conditions

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