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however, concomitant muscle mass loss is common, raising concerns about sarcopenia

Moreover, the efficacy of these drugs in MC4R KO mice aligns with clinical studies, indicating that MC4R KO mice serve as a reliable animal model for obesity research.

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During a presentation at the American Association of Clinical Endocrinology Annual Scientific and Clinical Conference, Justin Do, DO, an endocrinology fellow at Loma Linda University Medical Center in

We also discuss combination therapies and strategies to mitigate muscle mass loss during treatment and calls for targeted research, improved clinical education, and policy reforms to optimize the translational potential of GLP-1R agonists in both individualized care and population health
