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Regarding blood sugar control , these medications work through multiple complementary pathways

they work especially well for people with normal to overweight BMI who don't need dramatic results

This is the direct mechanism by which MOTS-c improves insulin sensitivity

Glycaemic improvements with GLP-1 receptor agonists typically occur more rapidly than weight loss effects

Hormonal fluctuations related to fat loss, combined with the effects of changing estrogen levels on the hair cycle, create additional vulnerability

One would expect that these treatments need to be continued for life, just in the same way as blood pressure medication, Dr Jebb said