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Conflict of interest The authors declare no conflict of interest Authors contributions Conceptualization, formal analysis, original draft preparation (SKC), writingreview and editing (SKC, DC), supervision, project administration, and funding acquisition (SKC)

Specific modulation of PNPLA3 activity through RNAi integrates a potentially effective therapeutic approach for the treatment of MASH

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This partial reversal may be driven by factors such as compliance challenges, waning drug efficacy, or measurement limitations

6 (calculated mass=4,224.6 Da, observed mass=4,224.0 Da)