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In clinical trials, liraglutide was compared with semaglutide in adult patients without diabetes with a body mass index (BMI) of 30 or more

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NICE Technology Appraisal 875 recommends semaglutide 2.4 mg (Wegovy) as an option for weight management in adults with a BMI of at least 35 kg/m (or 32.5 kg/m in certain ethnic groups) and at least one weight-related comorbidity

Common reactions include nausea, constipation, diarrhea, and bloating