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Description
However, endogenous GLP-1 has an extremely short half-life due to rapid degradation by dipeptidyl peptidase-4 and renal clearance
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The most promising compounds, 39 and 40 (Figure 6), showed an IC 50 of 2.80 nM against DPP-4 catalytic activity, with 20 - 40-fold selectivity over the DPP-8 and DPP-9 isozymes
Gallbladder Disease Including gallstones and inflammation of the gallbladder (cholecystitis)
A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
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