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This is achieved by virtue of their metabolic effects and reduction of body weight through their central actions of increased satiety and reduced food intake (see Figure 1), thus rendering them highly effective therapies

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The perpetrator drug is the drug which affects the pharmacokinetics of the other drug

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PRODIGY: a web server for predicting the binding affinity of proteinprotein complexes

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The results include a slimmer physique and significant improvements in key health markers, such as blood pressure and cholesterol

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But the landscape is confusing

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Based on sphingolipid biochemical pathways, sphingosine (So) and ceramide (Cer) can interconvert, and ceramide is further modified to become sphingomyelin (SM) or glucosylceramide (CerG1)

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