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CAPS Task Force recommendations (2020) and real-world experience support this stepwise approach

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This finding supports the role of glucose toxicity in DM-related dopaminergic dysfunction and cognitive impairment, suggesting that advanced glycation end products (AGEs) and their precursor methylglyoxal (MGO) are linked to cognitive impairment and changes in the dopaminergic system

doi: 10.1016/s0140-6736(65)92278-6

May Help With Medication Tolerance : Being well-hydrated may help your body adapt more comfortably to the medication, improving your ability to stay consistent with treatment

and forming microspheres by fusion of a GLP-1 receptor agonist with poly(d,l-lactide- co -glycolic acid) [17]
