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Ohn JH, Kwak SH, Cho YM, et al

Published studies with metformin use during pregnancy have not reported a clear association with metformin and major birth defect or miscarriage risk [see Data]
Thus, it is important to understand whether SMG may, in addition to weight loss, also have any beneficial impact on the risk of cardiovascular disease or events

In the US, Wegovy, which has been specifically approved for weight loss by the FDA, carries a warning to professionals to monitor for suicidal thoughts and discontinue the medication if necessary

As cheaper versions become widely available, adherence and continuity of care could become major concerns
Personnel must be adequately qualified and receive ongoing training to perform their duties competently
