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In contrast, multiple large trials demonstrate that combining a single GLP-1 agonist with a SGLT2 inhibitor (e.g., dapagliflozin, empagliflozin) provides synergistic cardiovascular and renal protection without redundant receptor targeting

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Diabetes Metab Syndr Obes 2015;8:241253 [DOI] [PMC free article] [PubMed] [Google Scholar] 43.Frias JP

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