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placebo) Adverse events were consistent with those observed in other clinical trials for other incretins, the most common among participants treated with retatrutide (9 mg and 12 mg, respectively) being nausea (38.1% and 43.2% vs 10.7% with placebo), diarrhea (34.7% and 33.1% vs 13.4% with placebo), constipation (21.8% and 25.0% vs 8.7% with placebo), vomiting (20.4% and 20.9% vs 0.0% with placebo), and decreased appetite (19.0% and 18.2% vs 9.4% with placebo)

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But they also have been found to have a significant impact on taste

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The injection site selection and technique principles mirror those for semaglutide and tirzepatide

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