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It would be fair to expect that GLP-1s, given they fall into both categories, will be a focus

The survodutide comparison is worth noting here too, as survodutide is another glucagon-containing dual agonist that shows strong liver fat effects

Mistake 5: Ignoring muscle

Adeniron E et al

Existing GLP1R agonists come with boxed warnings of thyroid cancer and pancreatitis, based mainly on rodent studies, where the effects of GLP1R agonism have noted species differences (For example, weight loss in rodents is mainly due to increased energy expenditure, whereas in humans it occurs via less food intake [54] )

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