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This review synthesizes animal and clinical evidence on leptins role in obesity, focusing on models such as genetically deficient mice (e.g., ob/ob , db/db ), diet-induced obesity mice, and clinical conditions such as congenital leptin deficiency (CLD), leptin receptor deficiency (LRD), lipodystrophy, and common obesity

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Therefore, the present study employs rsFC and ReHo analyses to explore treatment-related changes in neural activity

[Google Scholar] 155.Dekker I.M., van Rijssen N.M., Verreijen A., Weijs P.J., de Boer W.B.E., Terpstra D., Kruizenga H.M