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We assessed the prespecified secondary outcome metabolic syndrome severity z-score (MetS-Z), abdominal obesity (estimated as android fat via dual-energy X-ray absorptiometry), and inflammation marker high-sensitivity C-reactive protein (hsCRP)

I surveyed 90+ people on how GLP-1 messaging has affected their body image, mental health, and daily life

A mitochondrial switch ("SLC25A45") controls whether mitochondria burn fat or carbohydrate, and removing it (in mice) makes GLP-1 drugs stop working for fat loss entirely

Users of GLP-1 drugs such as Ozempic are seeking out protein, smaller portion sizes, hydration, and foods that soothe nausea, says Mattson.

We delineate how systemic metabolic dysfunction, often associated with obesity, synergizes with local inflammation to alter the balance between MMPs and their tissue inhibitors TIMPs, thus contributing to a perpetuating circle of inflammation and fibrosis

NONE of it addresses or improves the process for GLP-1s for Obesity