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Certain medications that are not primarily approved for obesity management but share the same chemical drug under different brand names and labels were separately analyzed in the study to explore potential off-label applications of GLP-1RAs

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When we treated the slices with 100 nM tertiapin-Q, a GIRK channel blocker, membrane potential was depolarized by 2.90.3 mV (from 52.42.1 to 49.51.9 mV, n =4) in four of seven POMC neurons (50%) (Fig