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Motulsky, H

Low NAD+ links to age-related diseases like cardiovascular issues, metabolic disorders, neurodegeneration, and cancer.[3][16] For example, in Alzheimer's models, NAD+ depletion exacerbates amyloid plaque formation and neuronal death

Staying well-hydrated, eating light and balanced meals, and avoiding heavy or greasy foods may help reduce early side effects like nausea

Delayed complications include acute gastritis (stomach lining inflammation), acute kidney injury from dehydration, and in rare cases, acute pancreatitis with elevated lipase and amylase enzymes

Boosting insulin production improves blood glucose control, particularly after meals

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