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Finally, although the alterations in ghrelin and GLP-1 signaling following bariatric interventions have been widely investigated, the direct causal contributions of these physiological changes to alterations in food reward-associated behaviors remain to be determined

Gastrointestinal side effects, including nausea, vomiting, diarrhea, and abdominal discomfort, are commonly reported, particularly during the initial weeks of treatment or following dose escalation

Pharmacy availability affects which formulations can be dispensed at the time of approval

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Compounded and microdose GLP-1 medications are not FDA approved

Weight loss injections, particularly glucagon-like peptide-1 (GLP-1) receptor agonists, can significantly impact gastrointestinal function