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Pharmaceutical Executive: How do you see the FDAs intent to take action against non-FDA-approved GLP-1 products affecting the competitive landscape for obesity and diabetes therapies in the near term

Absolute risk reduction: 1.3% Death from CV causes occurred in fewer patients in the Victoza group (219 patients [4.7%]) than in the SOC group (278 [6.0%]) (hazard ratio, 0.78
The glucagon-like peptide-1 receptor agonist reduces inflammation and bloodbrain barrier breakdown in an astrocyte-dependent manner in experimental stroke

Another approach employed to increase levels of endogenous GLP1 is the inhibition of DPP4, an enzyme responsible for the degradation of GLP1 and other peptides, by compounds such as sitagliptin

[DOI] [PubMed] [Google Scholar] 202.Gao, Y

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