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For anti-obesity GLP-1s, Medicares policy of not covering AOMs means that utilization skews heavily Commercial

Retatrutide hit 28.3% weight loss in the May 2026 trial

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Methods Using Danish nationwide registries, we emulated a target trial to assess the real-world effectiveness of GLP1-RAs in a population of individuals with type 2 diabetes mirroring the inclusion and exclusion criteria from the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER) trial