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Mr Jorgenson acknowledged that demand for the treatments was "putting strains on health care systems"

Not only does significant weight loss itself contribute to a deflated bottom when the subcutaneous fat under the skin gets smaller, but Amir Ghaznavi, a board-certified plastic surgeon in Herndon, Virginia, tells the Daily Beast that GLP-1s have been shown to decrease the amount of Type I collagen in the skin, which causes a sagging effect

There is no physiological dependence that makes sudden discontinuation dangerous for most people