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where this is particularly severe, nonsurgical methods are unlikely to be sufficient to fully address patient needs, and surgery should be discussed as a potential alternative (with nonsurgical procedures as possible adjuncts)

[1] Renal function should be monitored if significant gastrointestinal symptoms or dehydration occur

In fact, the European Medicines Agency's assessment report notes that co-administration with omeprazole produces a small, non-clinically meaningful increase in semaglutide exposure

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This is a standard rule across compounded prescription medications, not a policy specific to altRx