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A 10-pound goal typically takes 510 weeks, though individual timelines vary

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[5] The SURMOUNT-4 trial showed similar patterns for tirzepatide: patients switched from the drug to placebo regained about 14% of body weight over the following year, effectively erasing most of their loss

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Gastrointestinal side effects were most common: nausea (43%), diarrhea (33%), constipation (25%), and vomiting (21%) at the 12mg dose

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