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GLP-2 analogs are already approved therapies for short bowel syndrome and are effective at reducing the need for parenteral nutrition in ~65% of individuals 16

Initially, clinicians prescribed these medications primarily for glycemic control in patients with type 2 diabetes

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55 Another reported side effect to 0.5mg weekly semaglutide was a non-pruritic, non-blanchable, non-raised, painless petechial rash

The 2023 ADA guidelines recommend GLP-1 receptor agonists to reduce cardiovascular risk in individuals with a history of atherosclerotic cardiovascular disease (ASCVD), including myocardial infarction and stroke (22)

Most of these visits (69.3%) were due to severe gastrointestinal adverse reactions