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Insoluble fiber adds bulk and keeps digestion moving

NICE recommends GLP-1 therapy for type 2 diabetes (NG28) when: HbA1c remains elevated despite dual therapy with metformin and another oral agent The patient has a BMI of 35 kg/m or higher (or lower thresholds for certain ethnic groups) Significant weight loss would benefit other obesity-related comorbidities Insulin therapy poses specific risks or is declined by the patient For weight management, NICE has approved specific GLP-1 receptor agonists through Technology Appraisals

But when you'll actually start feeling the effects of stopping is a different question

According to the website, this includes guidance on administration, side effect management, and dose-related questions

That additional mechanism is one reason retatrutide has attracted so much interest

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