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NICE guidance recommends these as first-line treatments for osteoarthritis of the knee or hand

10.1200/jco.2008.17.9291 [DOI] [PMC free article] [PubMed] [Google Scholar] Park B., Bakbak E., Teoh H., Krishnaraj A., Dennis F., Quan A., et al

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Importantly, the administered treatment doses showed no notable effects on the animals body weight or signs of cytokine-related toxicity

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