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Clinical trials have shown that injectable GLP-1 agents generally produce slightly greater reductions in HbA1c

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Lee: Patient behavior can absolutely play a role

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Nathan BM, Rudser KD, Abuzzahab MJ, Fox CK, Coombes BJ, Bomberg EM, et al

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Still, others find the side effects unmanageable or find the medications to be ineffective

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However, despite only differing by 2 of the 39 residues (Gly 2 , Glu 3 in Ex4, compared with Ser 2 , Asp 3 in exendin-3), Ex4 was found to have distinct pharmacological properties and does not act at VIP or secretin receptors

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