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GLP3-R GLP1-S Safety and Side Effects in Research In controlled studies, GLP1-S has generally been well-tolerated , though gastrointestinal events are among the most common findings

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Initially, the team at Novo considered several different approaches, but opted to make a more stable version of GLP-1(7-37)

We selected nausea, vomiting and diarrhea, widely recognized as adverse effects of GLP-1 RAs, as positive outcome controls [43]