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Second, improvements in IR and glycaemic indices are most apparent in higher-burden phenotypes, particularly in women with impaired glucose tolerance/prediabetes or related metabolic comorbidities, where changes in HOMA-IR, fasting glucose and OGTT profiles are more pronounced and may plausibly reduce periconception metabolic risk

It is also pragmatic to determine if the same treatment approach can be used in idiopathic and in diabetic gastroparesis, or whether these conditions need to be treated differently

doi: 10.1210/clinem/dgad471 63 KielgastUKrarupTHolstJJMadsbadS

doi: 10.1007/s11033-014-3302-7

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The glucagon receptor component may help preserve lean mass through its effects on amino acid metabolism and protein turnover