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Concerns about thyroid cancer risk and the potential for sarcopenia or bone fragility in older patients further underscore the need for long-term surveillance (Nunn et al., 2024)

Specific antagonists were given 2 h before glucose at 1,500 nmol kg 1 doses, and tirzepatide was given 1 h before glucose, all by intraperitoneal injection

Baseline MDS-UPDRS part III scores averaged around 15 in both groups

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For these patients, a GLP-1 that produces large rapid weight loss without a muscle preservation strategy is trading one metabolic problem for another

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