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We dont have a definitive answer yet, but heres what we do know: Using GLP-1s for at least 12 months improves outcomes Stopping often leads to weight regain
Recently, in a mouse model of diabetic HFpEF, Withaar et al
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When GLP-1 medications slow those natural contractions, insoluble fiber helps compensate by providing the mechanical stimulus your colon needs to keep moving
However, their biological effects extend beyond appetite suppression
