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GLP-1 receptor agonists have been shown to reduce major adverse cardiovascular events including cardiovascular death, heart attack, and stroke in patients with type 2 diabetes

Many patients who experience severe nausea jumped to a higher dose too quickly or did not allow adequate time between dose increases

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The absolute risk difference was an additional 27 (range 17-38) events per 100,000 patients per year

The injection is stable for up to 28 days at room temperature or in the refrigerator from that first-use date

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