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Can I switch to semaglutide if tirzepatide is causing weight gain

Ultimately, the choice between the two will depend on factors like an individual patients needs, medical history and insurance coverage

Thats the cellular argument

The mRNA for GLP-1 receptors has been detected in all four chambers of the heart, and the GLP-1 receptor protein is significantly expressed in the sino-atrial node [34]

"I think it really is important now more than ever that we figure out a way to do a better job as physicians to check in on things like side effects, on things like muscle loss, on things like, 'how are your lifestyle changes going?' to make sure that our patients are safe," Guevarra said

In fact, patients experienced improved metabolic markers including reduced inflammation and blood pressure, which typically improve fluid distribution and reduce edema risk