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A 2024 Swedish study followed 3,249 MS patients for an average of 10.6 years and found that obesity was associated with: 4 43% higher risk of reaching EDSS 3 (moderate disability) 40% higher risk of reaching EDSS 4 (significant walking impairment) More rapid cognitive decline Higher MRI activity showing new brain lesions A German study of 1,066 MS patients found that obese patients reached disability milestones more quickly than those with normal weight

To treat constipation while taking a GLP-1 RA, start by increasing fiber and water intake and engaging in physical activity

[3] Regain happened despite ongoing lifestyle intervention in both groups
Our tirzepatide dosing for weight loss in units guide breaks down exactly how many units correspond to each milligram dose depending on the vial concentration

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