history of glp 1 agonists Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions GLP-1 Agonists Weight Loss Drugs

Guidelines have evolved considerably from routine medication cessation in 2023 to GLP-1 RA continuation with individualised risk assessment in 20242025, illustrating increasing acknowledgment that certain theoretical risks may be underestimated

Stress management and cortisol control Chronic stress elevates cortisol, which promotes abdominal fat storage, increases insulin resistance, and drives cravings for high-calorie comfort foods

Impact of GLP-1 receptor agonists on major gastrointestinal disorders for type 2 diabetes mellitus: a mixed treatment comparison meta-analysis

10.1016/j.cmet.2013.04.008 [DOI] [PubMed] [Google Scholar] 6.Sun L, Zheng ZM, Shao CS, Zhang ZY, Li MW, Wang L, Wang H, Zhao GH, Wang P (2022) Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

L.LasseterK

Vadher K, Patel H, Mody R et al (2022) Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: an adjusted indirect treatment comparison