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Home Wirkstoffgruppen Glucagon-like peptide 1 (GLP-1-)Rezeptoragonisten (Inkretinmimetika) werden zur Behandlung von Diabetes mellitus Typ 2 in Kombination mit anderen Antidiabetika oder als Monotherapie, wenn Metformin nicht indiziert ist, eingesetzt

Adverse Reactions/Side Effects The following adverse reactions are also discussed elsewhere in the labeling: Lactic Acidosis [see Warnings and Precautions (5.1)] Pancreatitis [see Warnings and Precautions (5.2)] Heart Failure [see Warnings and Precautions (5.3)] Acute Renal Failure [see Warnings and Precautions (5.4)] Vitamin B12 Deficiency [see Warnings and Precautions (5.5)] Hypoglycemia with Concomitant Use with Insulin or Insulin Secretagogues [see Warnings and Precautions (5.6)] Hypersensitivity Reactions [see Warnings and Precautions (5.7)] Severe and Disabling Arthralgia [see Warnings and Precautions (5.8)] Bullous Pemphigoid [see Warnings and Precautions (5.9)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

A1C Reduction: Rybelsus -1.8% vs Metformin -1.5% Both medications are effective at lowering blood sugar levels, but Rybelsus has a slight edge

My goal is to help patients find a treatment plan that is realistic, medically appropriate, and sustainable long term. Dr

June 10, 2024

Reported Side Effects (Phase 3 TRIUMPH-4 Data) Dysesthesia: The New Safety Signal Dysesthesia is an abnormal sense of touch where normal sensations feel unusual, uncomfortable, or mildly painful