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While GLP-1 will be released from intestinal cells upon consumption of food, the amount of insulin release that is triggered by GLP-1 varies due to the time of day.[ref] Diet changes rhythm: A Western Diet, high in fat and sugar, is used in research studies to induce obesity in animal models

orlistat, IC 025 = 4.91) and positive (venlafaxine, IC 025 = 2.89) controls confirmed the internal validity of the database

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Furthermore, another study has highlighted the role of liraglutide in preventing depressive-like behaviors by enhancing hippocampal neuron synaptic plasticity (Weina et al., 2018)