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It is important to note that GLP-1 M includes both DPP4i and GLP-1-RA, which have different mechanisms of action

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Tirzepatide (Zepbound) is FDA-approved for weight loss, while Mounjaro (tirzepatide) is approved for diabetes

Recent research indicates additional neuroprotective processes via GLP-1-mediated enhancement of BBB integrity [76], which requires further evaluation

When retatrutide binds the glucagon receptor on cardiac cells, it activates adenylyl cyclase
