bmi for glp 1 GLP-1 agonists and changes in body mass and composition in adults with overweight or obesity with or without type 2 diabetes mellitus: a systematic review and meta-analysis Are you in the red

Additionally, researchers are investigating combination therapies that incorporate GLP-1 receptor agonists with other pharmacological agents

and Lamos E

Even if the drug caused fewer cravings, the instinct to use food or restriction to manage emotions was still there

Strategies to mitigate muscle loss Muscle talks to your gut during exercise: Physical activity triggers muscle release of IL-6 and other signals that actually boost GLP-1 production in the intestines, creating a natural feedback loop that supports metabolism

doi:10.1200/JCO.2026.44.19_suppl.138 Jajja S, Thukral J, Abdalla A, et al

Until that happens, we may need to accept that PBMs private-label strategies are less than ideal, but better than the alternatives