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Moreover, it supports the FDA in its effort to modernize the long-established 510(k) pathway by promoting the availability of up-to-date device predicates upon which subsequent device applications can be based, reflecting positive spillovers that are likely to encourage manufacturers to adopt current state-of-the-art technologies and modern standards of safety and effectiveness

Clinical data shows weight rebound is common after GLP-1 agonist cessation, but structured tapering, lifestyle reinforcement, and personalized monitoring may help minimize risk

The cost per patient achieving 5% weight loss was 3768.72 for semaglutide and 4718.66 for liraglutide, corresponding to a difference of 949.95 per patient
