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[46] reported that the GLP-1 analog exenatide increased hepatic mitochondrial respiration in high-fat fed mice in various respiratory states, such as LEAK, OXPHOS, and ETS

The mediating role of obesity in the development of depression in individuals with diabetes: a population-based study from NHANES 20052014

These therapeutic implications may extend beyond BED to include individuals with bulimia nervosa, night eating syndrome or addictivelike eating phenotypes, who may benefit from targeted GLP1RA therapy

A big study found that tirzepatide helped RA patients lose more weight than semaglutide

Nature 2001;411:805810

For researchers using compounded tirzepatide , the same principles apply