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How do GLP-1 RAs such as Semaglutide work
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An invited review in the New England Journal of Medicine stated it plainly: the positive cardiac and renal effects of GLP-1 receptor agonists are more than just improvement in ambient glucose concentrations, pointing to pleiotropic vascular actions as key contributors to the MACE reductions observed across LEADER, SUSTAIN-6, SELECT, and the other landmark trials
All of the data here are observational data and not experimental, Gerstein said
