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Key Safety Factors and Baseline Assessment for UC Patients Before starting GLP-1 therapy, patients with ulcerative colitis should have documented disease remission or stable, mild inflammation

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Following on that note, GLP-1 RAs exhibit strong antiapoptotic effects by activating the PI3K/Akt pathway, promoting cell survival by inhibiting proapoptotic factors such as Bax and caspase-3 and upregulating antiapoptotic proteins such as Bcl-2

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