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Dehydration, can be caused by gastric emptying suppressing the thirst cue as well as the hunger cue, can cause people to not drink fluids throughout the day as they usually would

GLP-1 medications can cause gastrointestinal side effects like nausea, vomiting, or diarrhea, which can lead to dehydration

To investigate the relative contribution of non-genetic factors that predict GLP1 medication efficacy, we fit a linear model to assess the combined effect of age, sex, pre-treatment BMI, drug type, drug dose and time on drug on total BMI loss (Supplementary Table 3)

If you wish to explore berberine as an adjunct to conventional treatment, discuss this with your healthcare team to ensure safe, coordinated care

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