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Treat initial VWAP tests as decision points

Retatrutide is an investigational medication not yet approved by the FDA
For individuals with obesity, type 2 diabetes, or cardiovascular risk factors, the documented benefits of GLP-1 medications on weight, blood sugar, cardiovascular outcomes, and in some cases kidney and liver health are substantial
They work by enhancing insulin secretion, delaying gastric emptying, and reducing appetite

Detailed information on these datasets was provided in Supplementary Table S1