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While peptide drugs have a wide range of therapeutic applications, their relatively short half-life has been a challenge, attributed to poor metabolic stability and a fluid dynamic radius below the glomerular filtration limit of the kidneys.

Novo Nordisk the manufacturer of several GLP-1 receptor agonists such as liraglutide and semaglutide has said that it envisages intermittent supply shortages over the next 18 months.

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