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In the large-scale STEP (Semaglutide Treatment Effect in People) clinical trials, which involved thousands of participants, shingles was not identified as a statistically significant adverse event

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Capehorn MS, Catarig AM, Furberg JK, Janez A, Price HC, Tadayon S, Vergs B, Marre M

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The risk of serious side effects increases in patients with hypoglycemia, kidney problems, and a high risk for allergic reactions