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Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic -cells in mouse models of -cell regeneration

This implies that effective treatments developed for a specific condition are likely to benefit other conditions in which similar mechanisms play a significant role

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Individual variation in metabolic response is significant

Scientists at Duke have discovered that pancreatic alpha cells, which were once thought to only secrete glucagon, also release another significant hormone called GLP-1