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In PIONEER, AKI was a safety event of interest, and reported in all papers (14, 1719, 21, 23)

Novo Nordisks semaglutide is expected to lose its patent protection in Canada, Brazil, India, and China in 20252026

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IBS-related pain is thought to be caused by lowered sensory threshold and disturbed smooth muscle activation, leading to visceral hypersensitivity

ASSESSMENT OF COST-EFFECTIVENESS The medication effectiveness of BMI reduction was measured in QALYs

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