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Despite this beneficial effect, the exact mechanism behind how GLP-1s improve kidney function in individuals with diabetes is not fully understood at this time

Upcoming changes A major global health issue, diabetes mellitus necessitates innovative approaches to improve patient outcomes

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We reported previously that Na + -dependent glutamine uptake triggered electrical activity and GLP-1 release from the L-cell model line GLUTag

Biochem Biophys Res Commun 291:13021308 Yasuda N, Inoue T, Nagakura T et al (2002) Enhanced secretion of glucagon-like peptide 1 by biguanide compounds